The Problem Most drug candidates (>70%) are poorly soluble resulting in poor bioavailability. Many technologies (e.g. spray dry dispersion, hot melt extrusion, liposomal, nano emulsion, nano crystals, etc.) have been developed to address this solubility concerns in NCE. However, all of these methods use chemicals that become a part of the drug. This can lead to potential drug product toxicity...
“The Sunday Family and I are forever grateful for the 86Fund, the work they do, and the opportunity they’ve given us. With their grant money, our team has been able to keep regular working hours and we were even able to bring two team members back to work. In these difficult times, it is grant and emergency fund programs like the 86Fund that are helping keep restaurants like ours alive, and we...
Ada Developers Academy and Community Credit Lab partnered to focus on increasing equity in tech. Ada Developers Academy is a non-profit, tuition-free coding school for women and gender diverse adults. Ada focuses on serving low income people, underrepresented minorities, and members of the LGBTQIA+ community in Seattle and the surrounding region. Community Credit Lab provides community-funded, 0%...
The 86Fund is an emergency fund that aids independent restaurants—with priority given to those owned by women and minorities—facing unprecedented hardship during the global pandemic. Support Restaurants According to Yelp, as reported in ReBusinessonline in September, 61 percent of San Francisco restaurants that closed due to COVID will not reopen. A gift through the 86Fund will provide vital...
In addition to our off-the-shelf service that lets anyone turn philanthropic capital into an impact investment, this year Realize Impact now also operates three philanthropic investment funds for three partners. The Decarbon8-US fund is for those who believe in the power of entrepreneurship and technology and wonder what more they can do to mitigate climate change. Created in partnership...
Denkyem provides access to affordable loans for black-owned businesses in the Puget Sound region (a.k.a. the Seattle Metropolitan Area). The loan terms are simple and unique: This is a black-owned business serving black-owned businesses, started in partnership with one of Seattle’s most active early-stage investors: Realize Impact provided a recoverable grant to Denkyem, providing them some...
Three months ago Realize Impact lent $105,804 to the Colorado Lending Source to provide them capital for the SBA’s Payroll Protection Plan loans (the “PPP”). Late last month, we were paid back, with interest. You’ve most likely read about the PPP loans in the news. This is a fund to make those loans possible to more Main Street businesses. What the news stories...
The coronavirus pandemic brings more than a healthcare crisis to Africa, it brings disruptions to the food supply chain that will likely cause widespread hunger and starvation. The food system is already far from ideal, with (at least) 40% of that food never being eaten due to post-harvest losses (Rockefeller Foundation studies). Adding to these issues are the friction of closed borders...
The Truss Fund is provides emergency, 0% interest loansof up to $100,000 to market-driven social enterprisesaiming to end global poverty and protect the planet. The Fund is designed for enterprises that have beenespecially hard-hit by the pandemic, and who are graduatesof the GBSI Accelerator at Miller Center. The Truss Fund is managed by Beneficial Returns, an impact investment debt fund that...
Fledge is a global network of conscious company accelerators and investment funds, helping entrepreneurs create impactful companies and co-ops at scale through intense, short programs filled with education, guidance, and a massive amount of mentorship. Each city runs (up to) one session per year. Each city’s program is a bit different from the others’, but all are focused on mission-driven for...